Sibi Sebastian Joseph

Department of Neurology, Nelson Mandela Academic Central Hospital (NMACH), Walter Sisulu University, Mthatha, South Africa

Publications

• Review Article   
  Rituximab in Refractory Myasthenia Gravis: A Systematic Review
  Author(s): Lourdes de Fatima Ibanez Valdes, Sibi Sebastian Joseph and Humberto Foyaca Sibat*
  
  Background: Despite Myasthenia Gravis (MG) is a chronic autoimmune disorder some spontaneous remissions can occur (4-17 years) even before introduction of immunosuppressant. For the past eighty years, remarkable progress in the therapy of MG has been, and currently this condition is one of the most treatable autoimmune disorders worldwide. However, an important number of cases remain refractory or present lack tolerance to steroids and other immune suppressants, in such situations monoclonal antibodies have been contributing to better outcome of that community. To determine the proportion of patients responding well to RTX or presenting adverse responses, complications, or fatal results, we performed a Systematic Review (SR) of the published articles on MG treated with RTX looking for safer and more effective treatment for RMG. Material and methods:.. Read More»
  DOI: 10.3371/CSRP.DLSS.011023

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