Mona N Al-Terehi
Department of Sciences, University of Babylon, IraqPublications
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Research Article
Impact of DNA Repair System Genes RAD-18 and XRCC1 Polymorphism in Depression Disorders Patients
Author(s): Mona N Al-Terehi*, Zahraa Haleem AlQaim and Arafat Hussein Aldujaili
The Depressive Disorders (DDs) it is one of the most widespread psychiatric pathology forms and the relation of DNA repair with DD still under investigation, the present study was conducted to detect the RAD-18 Arg302Gln (rs373572) and XRCC1 Arg399Gln (28152) G>A gene polymorphisms in the DD patients, allele specific PCR and PCR-CTTP were used, the results show the age of patients (38.10 ± 12.74) year with BMI (24.98 ± 3.96) kg/m2 have duration of disease (7.50 ± 7.70) years and of control was (38.36 ± 12.85) year with BMI (27.02 ± 4.44) Kg/m2, non-significant differences of family history and significant variations were observed to dietary and exercise in study groups. The genotyping The RAD-18 show two alleles (A and G) and two genotyping (AA and GG), the AA was found in all patients and in.. Read More»