Michele Fonseca Szortyka
Department of Psychiatry and Behavioral Sciences, Federal University of Rio Grande Do Sul, Porto Alegre, BrazilPublications
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Research
Inflammatory Markers and Reduced Response to Physical Intervention in Schizophrenia: A Controlled Study with Chronic Outpatients
Author(s): Michele Fonseca Szortyka*, Viviane Batista Cristiano, Felipe Schuch and Paulo Belmonte‐de‐Abreu
Introduction: Schizophrenia is a complex chronic mental health disorder; this disease also shows signs of systemic inflammatory injury and possible muscle damage. This study aimed to evaluate the effects of a 3-month aerobic physical intervention program on functional capacity, systemic inflammatory response, and muscle damage in patients diagnosed with schizophrenia in comparison with healthy controls. Method: This is a paired clinical trial of physical intervention with patients diagnosed with schizophrenia. Functional capacity was explored with a 6-Minute Walk Test (6MWT), the systemic inflammatory response was assessed High-Sensitivity C-Reactive Protein (hs-CRP), and muscle damage Creatine Kinase (CK) and lactate. Results: Forty-eight patients concluded the intervention (24 cases with mean age of 39.3 ± .. Read More»
DOI: 10.3371/CSRP.SMVC.081922