Mennatallah O. Zaki

Department of Pharmacology and Biochemistry, Horus University, New Damietta, Egypt

Publications

• Research Article   
  Evaluation of β Amyloids and Tau Protein Biomarkers for Alzheimer’s Disease in Serum of Alzheimer Patients
  Author(s): Mennatallah O. Zaki*, Saad Shawki El-Sherifi, Ali Ahmed Abou Elmaaty, Amr Y. Zakaria, Abdelrheem M. Zidan, Abdullrahman M. Mahmoud, Omar Sh. Ali, Hosam A. Ashour, Hazem M. Abo-ghotma, Maryam M. Abdelhakim, Nada F. Ahmed, Hussieny E. Abdelazim, Khaled Ashraf, Ahmed R. Atya, Ranya A. Elsady, Galal S. Mehrez and Marwa A. Abdel-Dayem
  
  Background: β Amyloids and tau proteins are well-known markers of Alzheimer's Disease (AD). The goal of this study was to investigate the difference in the amounts of β amyloids [Aβ(1-42) and Aβ(1-40)] and tau protein in the blood serum of AD patients and controls participants in order to find more usable non-invasive AD biomarkers. Materials and methods: Following medical assessments, physical examinations, and regular blood tests to rule out other known causes to memory impairment, a total of 25 AD participants, aged 50–84 years, and 25 healthy age-matched controls, were initially chosen. The Mini-Mental State Examination (MMSE) was used to assess cognitive impairment in all subjects, as well as standard magnetic resonance imaging. We used the ELISA technique to evaluate the blood serum l.. Read More»
  DOI: 10.3371/CSRP.ZMSS.022822

  Abstract HTML PDF