Hadeel Alaa Al-Rrubaei

Publications

• Research   
  The RAD-18 Arg302Gln (rs373572) and OGG1 Ser326Cys (rs1052133) Genes Polymorphisms in Systemic Lupus Erythematous Disease
  Author(s): Noora M. Hameed*, Sawsam Jassim Al-Harbi, Hadeel Alaa Al-Rrubaei and Mona N. Al-Terehi
  
  The Systemic Lupus Erythematous (SLE) disease is an autoimmune disease incidence by different genetic and environment factors, the present research study two DNA repair genes polymorphisms in SLE disease included RAD-18 Arg302Gln (rs373572) and OGG1 Ser326Cys (rs1052133) genes, the polymorphisms were detection using allele specific PCR and PCR-SSCP, patients were diagnostic by specialist physician then DNA was isolated from whole blood, the results show that The RAD-18 gene variation show non-significant differences between patients and control, tow genotyping (AA and AG) were observed and GG didn’t observed, the distribution of AA and AG were 95.29% of patients have AA while 92.85% in control GG appeared in 4.76% of patients and 7.14% in control (OR 0.6667, P value 0.6936). The OGG1 Ser326Cys (rs1052133) genes polymorphisms shows the.. Read More»
  

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